<P>Praise for the Second Edition:</P><I><P>"¿ this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study."</I> -<B><I>Biometrics</P></B></I><P>"<I>This impressive book contains formulae for computing sample size in a wide range of settings. One-sample studies and two-sample comparisons for quantitative, binary, and time-to-event outcomes are covered comprehensively, with separate sample size formulae for testing equality, non-inferiority, and equivalence. Many less familiar topics are also covered ¿</I>" ¿ <B><I>Journal of the Royal Statistical Society</I></B></P><P><B>Sample Size Calculations in Clinical Research, Third Edition</B> presents statistical procedures for performing sample size calculations during various phases of clinical research and development. A comprehensive and unified presentation of statistical concepts and practical applications, this bo