Smith and Williams' Introduction to the Principles of Drug Design and Action av H. John Smith, Hywel Williams

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Advances in knowledge and technology have revolutionized the process of drug development, making it possible to design drugs for a given target or disease. Building on the foundation laid by the previous three editions, <b>Smith and Williams¿ Introduction to the Principles of Drug Design and Action, Fourth Edition</b> includes the latest information on topics such as gene therapy, computer-aided design, and molecular techniques including proteomics. Using real-world examples that illustrate the principles of drug design, the author explores the discovery of lead compounds and their manipulation in the production of non-toxic, metabolically stable drug candidates that will interact with target receptors in a predicted fashion. <p>See what¿s new in the Fourth Edition: <p>Fully updates and expands the contents <p>Coverage of agonists and antagonists of neuro-transmitters <p>Information on the design of stable peptide-like drugs <p>The human genome and its impact on drug discovery and deve