Network Meta-Analysis for Decision-Making av Sofia Dias, A. E. (School of Social and Community Medicine University of Bristol) Ades, Nicky J. (School

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<p><b>A practical guide to network meta-analysis with examples and code</b></p><p>In the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish which interventions are effective and cost-effective. Often a single study will not provide the answers and it is desirable to synthesise evidence from multiple sources, usually randomised controlled trials. This book takes an approach to evidence synthesis that is specifically intended for decision making when there are <b><i>two or more</i></b> treatment alternatives being evaluated, and assumes that the purpose of every synthesis is to answer the question "for this pre-identified population of patients, which treatment is ''best''?"</p><p>A comprehensive, coherent framework for network meta-analysis (mixed treatment comparisons) is adopted and estimated using Bayesian Markov Chain Monte Carlo methods implemented in the freely available software WinBUGS. Each chapter contains worked examples, exercise